Where it sits in the atlas: Thorne markets this powder for restful sleep and muscle relaxation, which is why it sits under Sleep & mind. That is the seller's positioning, not ours. This entry checks the label, the certification claim and the sleep research against it.
The short version
- One scoop (3.77 g) supplies 200 mg of elemental magnesium as magnesium bisglycinate, 48% of the Daily Value. The only other ingredients are citric acid and monk fruit concentrate.
- Trials of magnesium for sleep are small and contradict each other; the most recent systematic review (2026) rates the evidence low to very low certainty.
- $52.00 for the 60-scoop tub on Amazon on September 30, 2026, listed as in stock, shipped by Amazon and sold by a reseller. About $0.87 per scoop.
What the label shows
We read the Supplement Facts panel from the label image on the Amazon listing and compared it with the product page on thorne.com on September 30, 2026. The two match line for line. It is one of the shortest panels in this catalog.
| Ingredient | Amount per serving | What to know |
|---|---|---|
| Magnesium (as magnesium bisglycinate) | 200 mg (48% DV) | This is elemental magnesium, the number to compare with anything else. The Daily Value is 420 mg; the RDA is 310 to 420 mg a day for adults depending on age and sex[4][5]. |
| Magnesium bisglycinate (the compound) | not printed | Magnesium bound to two glycine molecules. A fully reacted bisglycinate is roughly 14% magnesium by weight, so 200 mg of magnesium implies something like 1.4 g of compound in the 3.77 g scoop. That is our arithmetic; the label does not state it. |
| Citric acid, monk fruit concentrate | not quantified | The whole "other ingredients" line. Monk fruit is the sweetener; there is no sugar, stevia, color or flow agent listed. |
| Calories, carbohydrate | not listed | The panel prints no calorie or carbohydrate line at all. |
The tub holds 7.98 oz (226.2 g) of powder, 60 scoops, and the listing describes it as gluten, dairy and soy free. Directions: mix one scoop in at least 8 ounces of water, once a day. On the seal: the tub and the listing both say NSF Certified for Sport, so we searched NSF's public Certified for Sport directory ourselves. It lists "Thorne® Magnesium Bisglycinate" as a powder with a 1-scoop (3.77 g) serving and a 7.98 oz (226.2 g) package, which is this exact tub; the entry carries lot numbers but no certification date[3]. (NSF also lists a 187 g tub and a stick-pack version under the same name.) Be clear about what that seal is: Certified for Sport tests lots for label accuracy, contaminants and a long list of substances banned in sport. It is not the USP Verified mark, and it says nothing about whether the product does anything.
What the evidence shows
Magnesium is an essential mineral, and most adults get it from food: leafy greens, nuts, seeds, beans and whole grains[5]. The question this tub raises is whether extra magnesium improves sleep in people who are not short of it, and the honest answer is that nobody has shown it convincingly. A 2021 meta-analysis found only three placebo-controlled trials in older adults (151 people in total). Pooled, they showed that falling asleep took about 17 minutes less with magnesium than with placebo, while total sleep time did not change significantly; every trial was rated at moderate-to-high risk of bias and the evidence as low to very low quality[6]. A 2023 systematic review found that observational studies link magnesium status to sleep quality but that the randomized trials contradict one another[7]. The most recent review we found, published in 2026, examined 12 randomized trials of magnesium given on its own. It concluded that results are inconsistent across questionnaires, EEG and wearables, that certainty is low to very low, and that the evidence does not support magnesium as a routine remedy for poor sleep, though some adults may see modest gains on some self-rated measures[8].
Dose is worth a look. The 2021 analysis describes its trials as giving under a gram of magnesium salt per dose, up to three times a day, and the 2026 review notes that elemental doses varied substantially between studies[6][8]. One scoop here is 200 mg of elemental magnesium, on the modest end of what has been studied and safely below the 350 mg a day Tolerable Upper Intake Level for supplemental magnesium[4]. Two scoops (400 mg) would go past that limit. As for the form: Thorne's own FAQ says glycinate and bisglycinate are two names for the same compound, and we did not find a trial comparing bisglycinate head-to-head with cheaper forms for sleep[2].
The 350 mg a day upper limit applies to magnesium from supplements, not food, and the first sign of too much is loose stools; Thorne's own label warns that gas, bloating or diarrhea can occur and resolve when the amount is reduced[2][4]. People with reduced kidney function should not add a magnesium supplement without a clinician's approval: the kidneys are how the body clears excess magnesium, and toxicity has occurred in this group[4][5]. Magnesium can also interfere with some antibiotics (quinolones, tetracyclines) and bisphosphonate bone medicines, so ask a pharmacist about spacing doses[4].
How it fits a daily routine
The label says one scoop in at least 8 ounces of water, daily. Thorne's FAQ suggests taking it 30 to 60 minutes before bed, with or without food, so it works as the last drink of the evening. The powder is lightly sweet and tart from the citric acid. If you already take a multivitamin, read its magnesium line before adding this; the two add up toward the supplement upper limit. It does not stack sensibly with a magnesium citrate or magnesium oxide product taken for regularity, because that is the same mineral twice. Melatonin is a different substance with different cautions and has its own entry. Keep antibiotics and bone medicines separated from it as noted above.
Price and where it is sold
On September 30, 2026 the 60-scoop tub (ASIN B0797HBLL3) was $52.00 on Amazon, listed as in stock, shipped by Amazon and sold by a third-party storefront called Pattern rather than by Thorne directly. That is about $0.87 per scoop, or $6.52 per ounce by Amazon's unit price; Thorne's own website listed the same tub at $52 the same day[2]. The 30-scoop version (ASIN B0DVZQKPVN) was $47.00 that day, nearly the same money for half the servings, so the 60-count is the better value unless you only want to try it. The listing carried a "non-returnable due to food safety reasons" note, the treatment Amazon applies to most ingestible products, with damaged or defective arrivals handled separately. Prices and return terms change; check the listing when you buy.
Who should look elsewhere
- Anyone with reduced kidney function, including people on dialysis, unless a clinician has approved a magnesium supplement.
- People taking quinolone or tetracycline antibiotics or bisphosphonate bone medicines, until a pharmacist has advised on timing.
- Anyone who wants a pill: this is a powder that needs a glass of water and a scoop.
- Anyone who wants an unsweetened product; monk fruit is mild but it is there.
- People who expect a proven sleep effect. The trials are small, inconsistent and low certainty.
- People who are pregnant or nursing: the label itself says to consult a practitioner first.
Sources
- Amazon.com listing for ASIN B0797HBLL3 (title, label images, price, availability and seller), viewed September 30, 2026. Not hyperlinked here; the Amazon button in the fact sheet opens the live listing.
- Thorne. Magnesium Bisglycinate product page: ingredient panel, directions, warnings, FAQ and price. Viewed September 30, 2026. link
- NSF. Certified for Sport product listing for Thorne Magnesium Bisglycinate powder, 1 scoop (3.77 g), 7.98 oz package. Viewed September 30, 2026. link
- Linus Pauling Institute, Oregon State University. Magnesium (Micronutrient Information Center): RDA table, the 350 mg supplemental upper limit, kidney-function caution and drug interactions. Updated July 2025, reviewed October 2025. link
- MedlinePlus (U.S. National Library of Medicine). Magnesium in diet: recommended amounts and the note on significantly reduced kidney function. Reviewed January 2025. link
- Mah J, Pitre T. Systematic review and meta-analysis of oral magnesium for sleep in older adults. BMC Complementary Medicine and Therapies, 2021 (correction 2024). PubMed record. link
- Arab A, et al. Systematic review of magnesium and sleep health. Biological Trace Element Research, 2023. PubMed record. link
- Lopresti AL, Smith SJ, Drummond PD. Systematic review of randomized controlled trials of magnesium supplementation for sleep in adults. Journal of Dietary Supplements, 2026. PubMed record. link
This entry is educational and is not medical advice. Ask a qualified clinician before starting any supplement, especially if you are pregnant, nursing, or take medication.